PERFORMANCE OF TWO HCV RNA ASSAYS DURING PROTEASE INHIBITOR-BASED TRIPLE THERAPY IN PATIENTS WITH ADVANCED LIVER FIBROSIS AND CIRRHOSIS.

Performance of two HCV RNA assays during protease inhibitor-based triple therapy in patients with advanced liver fibrosis and cirrhosis.

On-treatment HCV RNA measurements are crucial for the prediction of a sustained virological response (SVR) and to determine treatment futility during protease inhibitor-based triple therapies.In patients with advanced liver disease an accurate risk/benefit calculation based on reliable HCV RNA results can reduce the number of adverse events.However

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Narya, a RING finger domain-containing protein, is required for meiotic DNA double-strand break formation and crossover maturation in Drosophila melanogaster.

Meiotic recombination, which is necessary to ensure that homologous chromosomes segregate properly, begins with the induction of meiotic DNA double-strand breaks (DSBs) and ends with the repair of a MULTI BASICS-3 subset of those breaks into crossovers.Here we investigate the roles of two paralogous genes, CG12200 and CG31053, which we have named N

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